Toxic Impacts of Cypermethrin on Humans and Animals: A Review
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Published
Dec 29, 2025
Abstract
Pesticides are extensively used in modern agricultural practices worldwide, albeit in varying quantities. While their application has significantly contributed to enhanced crop yields, their widespread use poses considerable environmental, health, and safety risks to both terrestrial and aquatic ecosystems including humans, animals, and plants. Numerous existing and emerging pesticides have been shown to adversely affect the stability, growth, and survival of biological systems. A substantial body of research, utilizing various animal models for risk assessment, has explored the toxicological and biosafety profiles of these chemical agents. Among the different classes of pesticides, synthetic pyrethroids have become widely popular because of their strong insecticidal efficacy and comparatively lower mammalian toxicity than traditional organophosphate and organochlorine compounds. Cypermethrin, a type II synthetic pyrethroid, is extensively utilized in agriculture, veterinary medicine, and household pest management owing to its broad-spectrum effectiveness and cost efficiency. The toxicity of cypermethrin is influenced by multiple factors, including dosage, duration of exposure, and route of entry. Its environmental persistence and bioaccumulation further amplify the risk to non-target organisms, including humans and other terrestrial and aquatic life forms. This article provides a comprehensive review of the toxicological impacts of pesticides, with a specific focus on cypermethrin. It elaborates on the mechanisms of toxicity, public health implications, and its detrimental effects on humans and animals. The primary objective of this review is to consolidate current knowledge on cypermethrin toxicity and highlight its relevance in evaluating environmental and human health risks.
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Keywords
Cypermethrin, Toxicity, Human, Animals
Supporting Agencies
No funding source declared.
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How to Cite
Poli, V., & Motireddy, S. R. (2025). Toxic Impacts of Cypermethrin on Humans and Animals: A Review. Science Insights, 47(6), 2071–2086. https://doi.org/10.15354/si.25.re1237
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